Seeds As Repositories of Recombinant Proteins in Molecular Farming

News source: Rural Development Administration, Suwon, Korea
For further information, see Korean J. Plant Tissue Culture, v.27(4) pp.283-297., 2003-05-01

Role of P[Romoters in Seeds

Seeds are an ideal repository for recombinant proteins in molecular farming applications. However, in order to use plant seeds efficiently for the production of such proteins, it is necessary to understand a number of fundamental biological properties of seeds. This includes a full understanding of promoters, which function in a seed specific manner, the subcellular targeting of the desired polypeptide, and the final form in which a protein is stored.

Storage of Proteins in Seed

Once a biological active protein has been deposited in a seed, it is also critical that the protein can be extracted and purified efficiently. In this review, these issues were examined critically to provide a number of approaches, which may be adopted for the production of recombinant proteins in plants.

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